President ， Chief surgeon， Oncologist
Dr Niu Lizhi graduated from the Fourth Military Medical University with a doctoral degree in Thoracic & Cardiac Surgery. He is Vice President of International Society of Cryosurgery. He is supervisor of master degree course in Jinan University. Specialized in minimally invasive cryosurgery for cancers， he has made outstanding achievements in the treatment of pancreatic cancer， liver cancer， lung cancer， renal cancer， thyroid cancer， peritoneal cancer and other solid tumors with unique cryosurgery treatment approach. Dr Niu Lizhi and his team have performed most cases of cryosurgery (nearly ten thousand cases) and most complicated cryosurgery for cancer treatment in the world.
As the Chief Specialist for minimally invasive cryosurgery centre， Dr Niu Lizhi， together with his team， has made outstanding achievements and has provided cryosurgery training and guidance to more than fifty doctors from Malaysia， Indonesia， the Philippines， Korea， China’s Taiwan and the Southern Medical University， Xiangya Medical University and other hospital s in China.
Dr Niu’s patients aged from four year old child to 94 years old senior， ranking from Minister， celebrities， to ordinary people; all the treatments have been proved to be effective. Dr Niu Lizhi is praised by his patients as "The Number One Surgeon in the World "！
OFFICE ADDRESS
91，93 Jude Zhong Road
Chi Gang， Hai Zhu District
Guangzhou， China 510305
Fax： (+86)02034471406
Email： Niuboshi1966@yahoo.com.cn
EDUCATION
Degree-Granting Education
Faculty of Aviation Medicine， The Forth Military Medical University， Xi~an， China， MD.， 1989
Postgraduate Training
Clinical Resident， Chief Resident， Faculty of Thoracic Surgery， The Forth Military Medical University， 9/1989-7/1996
Ph.D.， Faculty of Thoracic Surgery， The Fourth Military Medical University， 9/1991-7/1996
CREDENTIALS
Board Certification
Vice professor of Chinese Thoracic Surgery， 9/2000
Diplomate of Chinese Surgery Oncology， 11/2006
Licensure
Chinese Medical License， Guangzhou， 1104400006670， 12/2007
EXPERIENCE/SERVICE
Academic Appointments
Attending Doctor， Associate Professor， Department of Thoracic Surgery， Southen Hospital， The First Military Medical University， 8/1996-1/2001
Administrative Appointments/ Responsibilities
President， President， Guangzhou Fuda Cancer Hospital， 1/2001-Now
Vice President， Guangzhou Fuda Cancer Hospital， 1/2001-1/2008
President， Guangzhou Fuda Cancer Hospital， 1/2008-Now
Consultantship
Korea Gunpo SAM Hospital/ Global SAM Integrative Cancer Center. International medical advisor， 8/2010
Institutional Committee Activities
Faculty Member， Cryosurgery Course of The International Society of Cryosurgery.
Executive member， Argon-Helium Targeted Cryoablation Committee of China Biological Medical Association
Executive member， Ultrasonic Intervention and Tumor Ablation Committee of Chinese Medical Doctor Association
Executive member， Medical Experts Committee of Chinese Retired Professor Association
Executive member， Radioactive Seed Implantation Committee of China Anticancer Association
Faculty Member， Minimally Invasive Committee of China Anticancer Association
Faculty Member， Chinese Society of Integrated Traditional Chinese and Western Medicine
Vice Director， Guangdong Cooperation Committee affiliated to Argon-Helium Targeted Cryoablation Committee of China Biological Medical Association
Executive member， Oncological Professional Committee of Guangdong Society of Integrated Traditional Chinese and Western Medicine
Executive member， Digestive Professional Committee of Guangdong Society of Integrated Traditional Chinese and Western Medicine
Faculty Member， Oncologist sub-commission of Guangdong physicians Society
HONORS AND AWARDS
Second prize of great sci-tech achievements in aviation logistics by project of “Basic research on Chest trauma” ，2005
Award of “Brilliant contribution to World Conference on Interventional Oncology” ， the 14th World Congress of Cryosurgery in Beijing ， 2007
Excellent Paper Award ， the 4th China South-North lung cancer peak forum by paper of “Treatment of unresectable pancreatic carcinoma with percutaneous implantation of 125lodine seeds”， 2008
Excellent Paper Awar， At the Ninth National Symposium on Interventional Diagnosis and Treatment 2009 by paper of “Combination of cryosurgery with 125iodine seed implantation for locally advanced pancreatic carcinoma”， 2009
Presidental Award， At the 36th Janpan Annual Meeting of Low Temperature Medicine， Tokyo， Japan， 2009
Outstanding Contributioner to Chinese Cryosurgery， World Cancer Congress 2010， Shenzhen， China， 2010
Third prize of excellent papers， by “Feasibility and Safety of Percutaneous Cryoablation for Locally Advanced Pancreatic Cancer” ， Guangzhou Anticancer Society，2010
RESEARCH Funded
Co-investigator， Modeling Research of Type I Neurofibroma Based on Technology of Inducing Multipotent Stem Cells， Natural Science Foundation of China， 81071901， 1/2011-12/2013，
Co-investigator， Analysis of Gene Spectrum of Familial pancreatic cancer， China 863 cancer genome project， 2006AA02A302， 6/2010-6/2011，
Co-investigator， Aternation of Tumor Markers of Malignant Tumor Before and After Cryoablation and Interventional Therapy， Regenerative biology laboratory foundation of the Chinese academy of sciences， KLRB201004， 11/2010-10/2012
Principal Investigator， Synthetic study of crysurgery for pancreatic cancer， Planning project of science and technology， Guangdong， WSTJJ20090401440106196602154756，2/2009-6/2011
Principal Investigator， Preliminary research of impact of cryoablation on chemo sensitivity of pancreatic cells， Planning project of science and technology， Guangdong， pending
Co-investigator， Four impacts in establishment of private hospital， Science and Technology Department， Guangdong， 2010B070300005， Completed
Co-investigator， Synthetic study of crysurgery for lung cancer， Science and Technology Bureau， Haizhu District， 2010-T-25， 7/2010-6/2012
PUBLICATIONS
Peer-Reviewed Original Research Articles
1. Xu KC， Niu LZ， He WB， Guo ZQ， Hu YZ， Zuo JS. Percutaneous cryoablation in combination with ethanol injection for unresectable hepatocellular carcinoma. World J Gastroenterol. 2003 Dec;9(12)：2686-9. (in Chinese)
2. Xu KC， Niu LZ， Hu YZ， He WB， Guo ZQ， Zuo JS. Percutaneous cryoablation combined with ethanol injection for unresectable hepatocellular carcinoma. Chin J Dig， 2003，23(9)：544-547. (in Chinese)
3. Xu KC， Niu LZ，Yang CB， Guo ZQ l. DC and anti-tumor therapeutic. JCPD， 2003(8)：20-23. (in Chinese)
4. Xu KC， Niu LZ，He WB， Guo ZQ， Zuo JS. Percutaneous ablation for liver cancer. Medern Dig Interv， 2003，8(4)：185-192. (in Chinese)
5. Niu LZ，He WB， Hu YZ， Guo ZQ， Zuo JS， Xu KC. Percutaneous implantation of I125 seeds for unresectable pancreatic cancer. Medern Dig Interv， 2003，8(4)：206-207. (in Chinese)
6. Xu KC， Niu LZ， Guo ZQ， Zuo JS. The application of hotodynamic therapy in digestive system neoplasms. Gastroenterol， 2003，8(2)：110-115. (in Chinese)
7. Xu KC， Niu LZ， Zhou Q， He WB， Guo ZQ， Zuo JS. Sequential therapy consisted of transarterial chemoembofization-cryoablation-percutaneous ethanol injection for unresectable hepatocellular carcinoma. Medern Dig Interv， 2003，8(3)：128-129. (in Chinese)
8. Xu KC， Niu LZ，He WB， Guo ZQ， Zuo JS，Hu YZ. Sequential treatment of unresectable primary liver cancer by transatrerial chemoembolization followed percutaneous cryoablation. Medern Dig Interv， 2004，9(3)：134-137. (in Chinese)
9. Niu LZ， Guo ZQ， He WB， Ye YK， Zuo JS， Xu KC. Combination of photodynamic therapy and percutaneous cryoablation for non-small cell obstructive lung cancer. Intern Med Health Herald， 2004(20)：13-16. (in Chinese)
10. Xu KC， Niu LZ. Chemothereapy for advanced gastrointestional cancer. JCPD， 2004(4)：23-27. (in Chinese)
11. Guo ZQ， Niu LZ，He WB， Deng CJ. Photodynamic therapy for 10 patients with tougue cancer. Chin J Laser Med Surg， 2005，14(4)：269-269. (in Chinese)
12. Yang CB， Guo ZQ， Zuo JS， Niu LZ， Xu KC. Traditional chinese medicine for unresectable liver cancer. New J Trad Chin Med， 2005，37(9)：6-7. (in Chinese)
13. Guo ZQ，Guo DH， Niu LZ， He WB， Zhou Q， Xu KC. Case report of huge nodular hyperplasia by cryo- chemical ablation. Chin J Dig， 2005，25(7)：390-390. (in Chinese)
14. He TS， Niu LZ，He WB. The application of I125 seeds implantation for malignant cancer. J Med Res， 2006，35(1)：74-76. (in Chinese)
15. Niu LZ，He WB， He TS，Li YH， Ye YK， Xu KC. Clinical anlysis of 508 cases of lung cancer treated with cryoablations. Chin Transport Med J， 2006，20(1)：29-30. (in Chinese)
16. Guo ZQ， Niu LZ， He WB， Zuo JS， Xu KC. Combination of photodynamic therapy and percutaneous cryoablation for non-small cell obstructive lung cancer. Chin Transport Med J， 2006，20(1)：31-32，34. (in Chinese)
17. Zuo JS， Niu LZ， He WB， Hu YZ， Guo ZQ， Xu KC. Effects of percutaneous I125 seeds implantation for advanced pancreatic cancer. Chin Transport Med J， 2006，20(1)：33-34. (in Chinese)
18. Xu KC， Niu LZ， Zhou Q， He WB， Guo ZQ， Zuo JS. Sequential therapy of chemoembolization followed by cryoablation and ethanol injection for 51 cases of unresectable hepatocellular cancinoma. Chin Transport Med J， 2006，20(2)：136-137. (in Chinese)
19. Niu LZ， He WB， Guo ZQ， Zhang SP， He TS， Zuo JS， Xu KC. Percutaneous cryoablation for local advanced non-small cell lung cancer. Chin Transport Med J， 2006，20(2)：138-139. (in Chinese)
20. Xu KC， Zuo JS， Niu LZ， Guo ZQ. 1 case report of huge neck teratoma treated by nonoperative comprehensive therapy. Chin Transport Med J， 2006，20(2)：156-156. (in Chinese)
21. Zuo JS， Niu LZ， Deng CJ， Xie CY. Combination of endoscopic radiofrequency ablation and photodynamic therapy for unresectable obstructive lung cancer： 34 cases reports. Chin J Laser Med Surg， 2006，15(2)：102-106. (in Chinese)
22. Guo ZQ， Niu LZ， Xu KC， Xie CY. 1 case report of gastroscopy induced aspiration pneumonia. Chin J Endoscopy， 2006，12(11)：1232-1232. (in Chinese)
23. Guo ZQ， Niu LZ， He WB， Deng CJ. Phtodynamic therpay for tougue cancer： 20 cases reports. Chin J Laser Med Surg， 2007，16(5)：296-298. (in Chinese)
24. Yang CB， Yuan J， Zhou L， Zhang CD， Niu LZ， Zuo JS， Xu KC. Effects of Jian Pi Kang Fu Wan on the treatment of large intestinal cancinoma. J Emerg Tradit Chin Med， 2007，16(10)：1198-1199. (in Chinese)
25. Guo ZQ， Niu LZ，He TS， He WB， Xu KC. I125 seeds implantation for advanced bladder cancer. Traffic Med， 2007，21(3)：262-263. (in Chinese)
26. Xu KC， Niu LZ. Cryosurgery for hepatocellular carcinoma. WCJD， 2008，16(3)：229-235. (in Chinese)
27. Xu KC， Niu LZ. Cryosurgery for liver cancer. Chin J Gastroenterol Hepatol， 2008，17(5)：345-350. (in Chinese)
28. Qu LX， Niu LZ， Xian H， Mu F. Experience of minimal invasive cryosurgery for elder non-small cell lung cancer. Guangdong Med J， 2008，29(9)：1499-1500. (in Chinese)
29. Xu KC， Niu LZ， David C， Yang CB， Yang DM， Mu F， Zuo JS. Discussion on prolonging survival of patients with advanced cancer—How to earn a term survival for patients with advanced cancer？ World Oncol， 2008，7(3)：169-181. (in Chinese)
30. Xu KC， Niu LZ， Hu YZ， He WB， He TS， Zuo JS. Cryosurgery combined with radioactive seeds implantation for local advanced pancreatic cancer. Chin J pancreatol， 2008，8(1)：9-12. (in Chinese)
31. Xu KC， Niu LZ， Hu YZ， He WB， He YS， Li YF， Zuo JS. A pilot study on combination of cryosurgery and (125) iodine seed implantation for treatment of locally advanced pancreatic cancer. World J Gastroenterol. 2008 Mar 14;14(10)：1603-11.
32. Xu KC， Niu LZ， He WB， Hu YZ， Zuo JS. Percutaneous cryosurgery for the treatment of hepatic colorectal metastases. World J Gastroenterol. 2008 Mar 7;14(9)：1430-6.
33. Xu KC， Niu LZ， Hu YZ， He WB， He YS， Zuo JS. Cryosurgery with combination of (125)iodine seed implantation for the treatment of locally advanced pancreatic cancer. J Dig Dis. 2008 Feb;9(1)：32-40.
34. Niu LZ， Zhou HT， Cao B. Palliative treatment of cancerous sinus tract obstruction by hotodynamic therapy combined with stents： reports on 26 cases. Chin J Laser Med Surg， 2009，18(2)： 88-91. (in Chinese)
35. Liang，B， Yuan J， Wang H， Lu HX， Niu LZ， Yang DM， Xu KC. Cases report of 2 patients with hepatic tuberculosis who suspected with liver cancer. Gastroenterol， 2009;14(6)：381-383. (in Chinese)
36. Zhou HT， Niu LZ， Zhou L， Mu F， Zhang CM， Liang B， Yang DM， Xu KC. Variation of biochemical indicator and former inflammatory infactor of patient with hepatocellular carcinoma after treated with cryoablation. Chin J Gastroenterol hepatol， 2009;18(2)：110-112. (in Chinese)
37. Xu KC， Niu LZ， Hu YZ， Mu F， Zhou L， Li YF， Yang DM， Zuo JS. cryosurgery combined with I125 seeds implantation for local advanced pancreatic cancer. Chin J Dig， 2009;29(4)：260-263. (in Chinese)
38. Xu KC， Niu LZ， Zhou L，Hu YZ， Guo DH， Liu ZP， Liang B， Mu F， Li YF， Zuo JS. Sequential use of transarterial chemoembolization and percutaneous cryosurgery for hepatocellular carcinoma. WJG， 2009;15(29)：3664- 3669.
39. Niu LZ， Liang B， Zhou HT， Zhang LX， Peng X， Xu KC. case report of huge malignant mesothelioma treated with comprehensive treatment. Chin J Cancer Prevent Treat， 2009;16(24)：1977-1978. (in Chinese)
40. David C， Niu LZ， Mu F， Zhou L， Li HB， Li RR， Xu KC， Ni JZH， Jiang LZ， Hu YZ， Hao ZHF. Experimental research of safety and efficacy of cryoablation on pancreas. Chin J Pancreatol， 2010，10(2)124-127. (in Chinese)
41. David C， Niu LZ， Mu F， Peng X， Zhou L， Li HB， Li RR， Ni JZH， Jiang NZ， Hu YZ， Hao ZHF， Xu KC. The experimental study for efficacy and safety of pancreatic cryosurgery. Cryobiology， 2010，60(3)：281-286.
42. Niu LZ， Xu KQ， Liang B， Wang F， Zuo JS， Xu KC. “cryoshock”induced by cryoablation--3 cases report. Contempor Med (Chin Interv Radiol)， 2010，16（5）：119. (in Chinese)
43. Niu LZ， Xu KQ， Liang B， Wang F， Zhou L， Zuo JS， Xu KC. Cryoshock happened in patient with hepatic metastasis. Modern Dig Interv， 2010，15(2)：122-124. (in Chinese)
44. Niu LZ， Wang J， Zhou L， Wu BH， Mu F， Li HB， Hu Y， Hu YZ， Zuo JS， Xu KC. Complications of cryoablation in 644 lung cancer patients and its treatment. Chin J Lung Cancer， 2010，13(8)：832-834. (in Chinese)
45. Niu LZ， Wang J， David C， Zhou L， Wu BH， Fang G， Tang J， Mu F， Li HB， Mei BJ， Deng CJ， Deng CM， Hao ZHF， Xu KC. Imaging and pathological features of percutaneous cryosurgery on normal lung evaluated in a porcine model. Chin J Lung Cancer， 2010，13（7）：676-680. (in Chinese)
46. Niu LZ， Li HB， Weng WF， Hu Y， Wu BH， Liang B， Li RR， Zhou L， Wang J， Yang DM， Xu KC. Feasibility and safety of percutaneous cryoablation for locally advanced pancreatic cancer， Chin J pancreatol， 2011， 11(1)：1-3. (in Chinese)
Other Articles
1. Zuo JS， Xu KC， Niu LZ，Liu JG， Wang YT， Ji L. Great significance of construction and development of Fuda Cancer Hospital. Modern Hospt， 2010，10（1）：4-6. (in Chinese)
2. Niu LZ， Xu KC， Yang DM， Mu F， Wu BH， Li HB， Ji L. Boost innovation of cancer treatment with advanced cryotechnique. Modern Hospt， 2010，10（1）：7-8. (in Chinese)
3. Xu KC， Zuo JS， Niu LZ， Liu JG， Mu F， Yang DM， Liao CY， Ji L. Stratege of Medical service differentiation in Fuda Cancer Hospital. Modern Hospt， 2010，10（1）：9-11. (in Chinese)
4. Niu LZ， Zuo JS， Liu JG， Yang KM， Mu F， Wang YT， Ji L. Leading by culture， promoting by ethics—construction concept of Fuda Cancer Hospital by Kecheng Xu. Modern Hospt， 2010，10（1）：12-13. (in Chinese)
Books (edited and written)
Xu KC， Niu LZ. Cryosurgery of Cancer. Shanghai ： Shanghai science and technology education publishing， 2007. (in chinese)
Book Chapters
Chai SD. Radioactive Seeds Implantation Therapeutics in Thoracic Cancer . Niu LZ， Combination treatment of lung cancer by radioactive seeds implantation and other minimal invasive therapies. Publishing. (in chinese)
EDITORIAL AND REVIEW ACTIVITIES
Editor/ Service on Editorial Board(s)
Editorial Board， Argon-Helium Targeted Cryoablation of Cancer， 2003-present (in chinese)
Editorial Board， Cancerous， Distortion， Mutation， 1989-present (in chinese)
Editorial Board， Chinese Journal of Minimal Invasive Therapy for Cancer， 2011-present (in chinese)
Journal Reviewer
Ad Hoc Journal Reviewer， Chinese Journal of Lung Cancer， 2010-present
CONFERENCES AND SYMPOSIA
Organization of Conferences/ Symposia (Include chairing session)
Vice Director， Academic Committee of The First World Tumor Cryotherapy Congress;
Vice Director， Academic Committee of The First China Minimally Invasive Therapy for Tumor.
Presentations at National or International Conferences
Invited
Cryoablation for central lung cancer， The 14th International Cryosurgery Conference， Beijing， China， 11/2007
Cryoablation combined with iodine-125 sed implantation to treat unresectable pulmonary cancer， The 35th Japan Annual Meeting of Low Temperature Medicine， Tokyo， Japan， 11/2008
Cryosurgery combined with radioactive seeds implantation for unresectable pancreatic cancer， The 4th Chinese South-North Summit Forum of Lung Cancer， Guangzhou， China， 11/2008
The application of cryosurgery in the treatment of advanced lung cancer， Seminar of therapeutic progress of thoracic cancer， Guiyang， China， 6/2009
Combination therapy of cryosurgery and I125 seeds for unresectable pancreatic cancer， World Conference of Interventional Therapy of Oncology 2009， Beijing， China ， 6/2009
The application of percutaneous cryoablation in cancer treatment， National Seminar of Minimal Invasive and Targeted therapy for Cancer， Inner Mongolia， China， 7/2009
Cryoablation for liver cancer， Shengzhen-Hongkong Digestive Disease Forum， Shenzhen， China， 8/2009
CT guided percutaneous cryosurgery for advanced lung cancer， The 3rd CSCO Biomedical and Molecular Targeted Therapy for Cancer cum Seminar of Advanced Progress of Comprehensive treatment for Cancer， Guangzhou， China， 8/2009
Radioactive seeds implantation combined with cryoablation for advancer hepatocelluar carcinoma， The 3rd National Conference of Radioactive Seeds Implantation of cancer， Qingdao， China， 8/2009
The application of cryosurgery in the treatment of advanced cancer， The 15th International Cryosurgery Conference， St. Peterstburg， Russia， 10/2009
Cryoablation for advanced colorectal carcinoma， The 9th National Seminar of Interventional Therapy of Digestive Malignant Tumor， Henan， China， 11/2009
Cryosurgery for lung cancer， The 3rd Asia Pacific Bronchoscope and Interventional Therapy for Lung Cancer Seminar， Guangzhou， China， 11/2009
Sequential therapy of chemical embolization and cryoablation for advanced hepatocellular carcinoma， The 3rd National Ultrasonagraphy Guided Interventional Therapy Conference， Guangzhou， China， 11/2009
Long term survival of a 94-year-old woman with advanced lung adenocarcinoma after cryoablation， The 36th Japan Annual Meeting of Low Temperature Medicine， Tokyo， Japan， 11/2009
Cryosurgery for lung cancer， The 1st China-Germany Lung Cancer Forum， Shanghai， China， 12/2009
Early diagnosis and treatment for lung cancer， The 3rd Recent Advances in Cancer Diagnosis Therapy， Jakarta， Indonesia， 4/2010
Complications of cryosurgery for lung cancer—clinical experiences from 3200 cases， The 4th National Minimal Invasive Treatment of Lung Cancer Forum， Guangzhou， China， 5/2010
Survival analysis of 151 patients with lung cancer following percutaneous cryotherapy & A novel cutaneous approach to deliver cryotherapy for the treatment of advanced pancreatic cancer， 2010 World Conference on Interventional Oncology， Philadephia， USA， 6/2010
Cryosurgery for pancreatic cancer & lung cancer， The 21st World Anti-cancer Conference cum 1st National Meeting of the Cryosurgery Group， Shenzhen， China， 8/2010
Feasibility of percutaneous cryosurgery for unresectable pancreatic cancer， The 9th China Intervention and Radiation Conference， Guangzhou， China，9/2010
Complication of cryosurgery， National Conference of Imagin Guided Interventional Therapy on Oncology， Beijing， China， 9/2010
Clinical experiences of cryosurgery in cancer treatment， The 1st International Cryosurgery and Interventional Ablation Seminar， Beijing， 11/2010
CT-imaging and pathological features of percutaneous cryosurgery on normal lung evaluated in a porcine model & Impact of Percutaneous Cryotherapy on Survival of Advanced Lung Cancer with or without Chemotherapy， The 37th Japan Annual Meeting of Low Temperature Medicine， Tokyo， Japan， 11/2010
Effects of CT guided percutaneous cryosurgery in the treatment of lung cancer， The 5th National Thoracic Tumor and Endoscope Conference， Haikou， China， 3/2011
Cryosurgery for head and neck cancer， The indonesian society of interventional radiological meeting， Surabaya， Indonesia， 4/2011
Other， Including Scientific Exhibitions
The application of cryosurgery combined with I125 seeds implantation for unresectable lung cancer & Cases report of complication of cryosurgery for pancreatic cancer， International Conference of brach radioactive seeds implantation of Cancer， Beijing， 9/2010
Survival analysis of advanced lung cancer treated by percutaneous cryosurgery， The 13th CSCO， Beijing， 9/2010
Cryosurgery ferformance， Ultrasonagraphy Guided Interventional Therapy for Cancer， Shanghai， 9/2010
Complications of Cryoablation：320 Cases of liver Cancer， The 21st conference of the asian pacific association for the study of the liver（APASL）， 12/2010
Seminar Invitation from Other Institutions
Cryosurgery for cancer， Sunday Symposium of the Society of Physicians of Hongkong， Hongkong， China， 9/2010
Cryoablaiton in cancer， Cancer Conference at Aarhus University， Danmark， 10/2010
Cryosurgery for cancer， Healthy lecture， Singapore， 11/2010
Lectureships and Visting Professorships
Guangzhou Institute of Biomedicine and Health， Chinese Academy of Sciences， China， 2011