光动力疗法联合支架置人姑息性治疗癌性腔道梗阻——附26例报告/Photodynamic Therapy Combined with Stent Implantation for Lumina Obstruction Caused by Cancers: 26 Case Report
NlU Lizhi, ZHOU Hongtao, CAO Bin et al.
【摘要】
目的：观察光动力疗法联合支架置入姑息性治疗恶性腔道梗阻的疗效及其并发症。
方法：26例腔道梗阻，失去手术机会或拒绝手术的中晚期癌症患者，包括15例食管癌、5例支气管癌，6例胆总管癌，行光动力疗法加支架置入姑息住解除腔道梗阻治疗。术后跟踪随访半年，观察疗效、并发症、KPS，定期内镜检查腔道通畅状况。
结果：26例患者，术后腔道梗阻明显缓解，仅1例食管癌患者发生支架移位，1例月嗵总管癌患者发生再次梗阻，KPS评分从平均31.0分提高至42.4分，并发症经相应处理后均症状消失。
结论：光动力疗法联合支架置入姑息性治疗能有效缓解癌性腔道梗阻症状，并发症少，能明显改善腔道梗阻患者的生存质量。
【关键词】光动力疗法；支架；癌症；梗阻
[Abstract]
Objective To observe the palliative therapeutic effects and complications of photodynamic therapy(PDT)combined with stent implantation on lumina obstruction caused by cancers．
Methods Twenty-six inoperable or refusing surgery lumina-obstructed patients，including 15 esophagous cancer，5 bronchial carcinoma and 6 choledochus cancer peteints received PDTcombined with stent implantation in order to palliatively relieve lumina obstruction．Patients were foUowed up half a year，the therapeutic effects，complications and Kamofsky point scale(KPS)were observed and recorded and the endoscope examination was performed periodically to observe the lumina obstruction．
Results All 26 patients successfully received PDTand stent implantation palliative therapy，hmina obstruction condition was obviously alleviated；of 26 patients，only one stent shifted in esophageous cancer patient and lumina reobstruction in one choledochns cancer patient occurred，the average KPS of patients elevated from 31.0 to 42.4，all complications were handled safely．
Conclusions PDTcombined with stent implantation palliative therapy can effectively alleviate lumina obstruction caused by cancers with rare much complications，and can notably improve life quality．
[Key words] Photodyanmic therapy；Stent；Cancer；Obstruction
